Standardized approval of fishery drugs Standardized production is the trend

Release time:

2023-09-25

The development of fishery medicine is closely related to the development of aquaculture, aquatic animal diseases and pharmacy, and is also influenced by modern life and management concepts. This paper puts forward some countermeasures and prospects for the confusion faced by the development of fishery medicine in China.
　　
Fishery drug residues in aquatic products have seriously affected the quality and safety of aquatic products. People's long-term intake of aquatic products containing fishery drug residues will affect their health. For example, sulfonamides can cause kidney damage, penicillin, tetracycline and other drugs will make sensitive people have allergic reactions, and severe cases can cause shock and other symptoms. The safety of aquatic products has aroused widespread concern in society, making countries more and more stringent in the formulation of fishery drug residue limits, China's aquatic product exports have repeatedly encountered green barriers, in recent years, the export of eel, crayfish and other aquatic products due to excessive drug residues were returned.
　　
The toxic and side effects of environmental protection fishery drugs on the ecological environment cannot be ignored. Foreign scholars have studied the concentration, duration and enrichment of many fishery drugs in the environment. Samuelsen and others found that after using oxytetracycline in Gulf fishing grounds, most of oxytetracycline in silt can be degraded in the first week, but the lower concentration residue can exist for a long time (half-life: 87-144 days). Wollenberger and others reported that commonly used antibacterial drugs such as oxytetracycline have acute toxic effects on Daphnia magna and have potential adverse effects on water environment. Chlorinated disinfectants contain a large amount of chlorinated disinfection by-products, these substances have been shown to be associated with tumorigenesis. However, domestic research is less involved, and there is still a lack of research on the accumulation and transfer of a large number of disinfectants and pesticides in water bodies.
　　
Drug resistance of pathogenic bacteria In the current aquaculture, chemical drug treatment of fish diseases has become a common phenomenon. However, the use range and dose of fishery antibacterial drugs are increasing day by day, and the problem of drug resistance of pathogenic bacteria in aquaculture water is becoming more and more serious. For example, the drug resistance test results of Zheng Guoxing and others on the aquaporin isolated from the skin ulcer of European eel showed that the drug-resistant strain rate to norfloxacin was 60.0, and the minimum inhibitory concentration (MIC) was as high as 128 μg/ml, which was dozens of times higher than the use concentration, increased the difficulty of aquatic animal disease control.

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The use of compound feed for intensive cultivation of mixed fish in ponds and ponds is a common breeding method in pond fish production at present, and the feed cost accounts for about 60-70% of the breeding cost. The feed coefficient, also known as the feed coefficient, refers to the ratio of the amount of feed fed to the total net increase in production of the aquaculture object. The smaller the ratio, the less feed is used to increase the unit yield of aquatic products, and the better the efficiency. Therefore, the key to reducing the feed cost of pond fish farming lies in reducing the feed (bait) coefficient. The smaller the ratio, the lower the feed coefficient, which reduces the feed cost and improves the economic benefits of aquaculture. Of course, the phrase "reducing feed coefficient" seems to be well-known to many people, and there are even many people who will say it, but.

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Small Knowledge of Feed Mold Prevention one

Hubei Lide Biological Engineering Co., Ltd.

Address: West Ring Road 4, Economic Development Zone, Zhongxiang City, Hubei Province
Telephone:0724-4933839 4933838
Mailbox:3231541693@qq.com
Production License (2022) Veterinary Drug Production Certificate No. 17055
Veterinary Drug GMP Certificate (2022) Veterinary Drug GMP Certificate No. 17018